LSBio
Human AREG / Amphiregulin Protein (Recombinant)

Human AREG / Amphiregulin Protein (Recombinant)

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Expression SystemHuman Embryonic Kidney 293
Format:Lyophilized
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$259.00each
Catalog Number: LS-G27177-10

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Overview

Description
Amphiregulin is a member of the EGF family of cytokines, which comprises at least ten proteins including EGF, TGF-a, HB-EGF, Epiregulin, Tomoregulin, Neuregulins and the various heregulins. Through the EGF/TGF-a receptor, it stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Amphiregulin | CRDGF | SDGF | AREG
Origin Species
Human
NCBI GenBank
NM_001657|NP_001648.1
SwissProt
P15514

Protein

Expression System
Human Embryonic Kidney 293
Molecular Weight
15~20 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR KKKNPCNAEF QNFCIHGECK
61YIEHLEAVTC KCQQEYFGER CGEKSMKTHS MIDSSLSK

98 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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