LSBio
Human ALDH3A1 Protein (Recombinant His)

Human ALDH3A1 Protein (Recombinant His)

ProteinLSBio Guarantee
Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
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$282.00each
Catalog Number: LS-G694-10

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Overview

Description
ALDH3A1, also known as Aldehyde dehydrogenase 3 family memberA1, is involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to uV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. Recombinant ALDH3A1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Aldehyde dehydrogenase 3 | ALDH3 | ALDH3A1 | ALDHIII | Stomach aldehyde dehydrogenase
Origin Species
Human
NCBI GenBank
NM_000691|NP_000682.3
SwissProt
P30838

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
11-453aa|MG SSHHHHHHSS GLVPRGSHMS KISEAVKRAR AAFSSGRTRP LQFRIQQLEA
61LQRLIQEQEQ ELVGALAADL HKNEWNAYYE EVVYVLEEIE YMIQKLPEWA ADEPVEKTPQ
121TQQDELYIHS EPLGVVLVIG TWNYPFNLTI QPMVGAIAAG NAVVLKPSEL SENMASLLAT
181IIPQYLDKDL YPVINGGVPE TTELLKERFD HILYTGSTGV GKIIMTAAAK HLTPVTLELG
241GKSPCYVDKN CDLDVACRRI AWGKFMNSGQ TCVAPDYILC DPSIQNQIVE KLKKSLKEFY
301GEDAKKSRDY GRIISARHFQ RVMGLIEGQK VAYGGTGDAA TRYIAPTILT DVDPQSPVMQ
361EEIFGPVLPI VCVRSLEEAI QFINQREKPL ALYMFSSNDK VIKKMIAETS SGGVAANDVI
421VHITLHSLPF GGVGNSGMGS YHGKKSFETF SHRRSCLVRP LMNDEGLKVR YPPSPAKMTQ
481H

481 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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