LSBio
Human ACTRIIB / ACVR2B Protein (Recombinant Fc)

Human ACTRIIB / ACVR2B Protein (Recombinant Fc)

ProteinLSBio Guarantee
Expression SystemOther
Format:Lyophilized
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$3289.00each
Catalog Number: LS-G97124-1

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Overview

Description
The recombinant human ACVR2B/Fc chimera is a disulfide-linked homodimer generated after removal of the signal peptide. The reduced monomer comprises 354 amino acids and predicts a molecular mass of 40.0 kDa. As a result of glycosylation, the monomer migrates as an approximately 60-65 kDa protein in SDS-PAGE under reducing conditions. A DNA sequence encoding the N-terminal segment (Met 1-Thr 134) from the extracellular domain of human ACVR2B (NP_001097.2) was expressed with the fused human IgG1 Fc region at the C-terminus.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Activin A receptor type IIB | Activin receptor type-2B | ActR-IIB | ACTRIIB | Activin receptor type IIB | Activin A receptor | type IIB | ACVR2B | HTX4
Origin Species
Human
NCBI GenBank
NM_001106
SwissProt
Q13705

Protein

Expression System
Other
Fusion Tag
Human IgG1 Fc Tag
Molecular Weight
40.0 kda
Protein Type
Recombinant
Amino Acid Sequence
1Met 1-Thr  134

13 aa

Format

Purity
>97%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1.0 EU/µg
Format
Lyophilized
Formulation
Lyophilized from sterile PBS, pH 7.4
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Store at -70°C.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.