CSF1 / MCSF Protein (Recombinant)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Lyophilized |
$302.00each
Catalog Number: LS-G26999-10
Catalog Number: LS-G26999
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- Description
- Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. Interaction of M-CSF with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of several types of cancer, including breast and endometrial cancer.Recombinant Rat Macrophage Colony Stimulating Factor (M-CSF) produced in E.coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 155 amino acids each. A fully biologically active molecule, rrM-CSF has a molecular mass of 28 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- CSF-1 | MCSF | M-CSF | CSF1 | Lanimostim | CSFM
- NCBI GenBank
- NM_000757|NP_000748.3
- SwissProt
- P09603
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Molecular Weight
- 28 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1Glu33-Pro1 86
12 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from 50 mM Tris-HCl, pH 8.0, 150 mM NaCl
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 3 months.