Immunohistochemistry of paraffin-embedded human adrenal gland tissue using ZRANB3 Antibody at dilution of 1:100

ZRANB3 Antibody

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C501014-50

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Description: ZRANB3 antibody LS-C501014 is an unconjugated rabbit polyclonal antibody to human ZRANB3. Validated for ELISA and IHC.
Application: ELISA, IHC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: Annealing helicase 2 | DKFZP434B1727 | AH2 | ZRANB3
UniProt Number: Q5FWF4
NCBI GenBank: NM_032143 | NP_115519.2
SwissProt: Q5FWF4

Target: Human ZRANB3
Antigen Species: Human
Epitope: DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the formation of double-strand breaks.
Gene Name: ZRANB3