Positive WB detected in:Mouse heart tissue,Mouse spleen tissue,Mouse lung tissue;All lanes: ZKSCAN3 antibody at 4?g/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;predicted band size: 61,44 kDa;observed band size: 61,44 kDa;
ZKSCAN3 / ZNF306 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C501696-50
Catalog Number: LS-C501696
For bulk orders or custom formulations:
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- Description
- ZNF306 antibody LS-C501696 is an unconjugated rabbit polyclonal antibody to ZNF306 (ZKSCAN3) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB. Cited in 1 publication.
- Application
- ELISA, IF, IHC, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- DJ874C20.1 | DJ874C20.1. | KIAA0426 | Zfp-47 | ZFP306 | Zinc finger protein 309 | ZNF306 | ZNF309 | ZSCAN13 | ZSCAN35 | ZF47 | Zinc finger protein 306 | Zinc finger protein zfp47 | Zfp47 | Zinc finger protein 47 homolog | ZKSCAN3
Target
- Target
- Human ZKSCAN3 / ZNF306
- Antigen Species
- Human
- Epitope
- Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Zinc finger protein with KRAB and SCAN domains 3 protein (8-275AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Concentration
- 4 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Alcohol-Induced Lysosomal Damage and Suppression of Lysosome Biogenesis Contribute to Hepatotoxicity in HIV-Exposed Liver Cells. Moses New-Aaron , Paul G Thomes , Murali Ganesan , Raghubendra Singh Dagur , Terrence M Donohue Jr , Kharbanda K Kusum , Larisa Y Poluektova, Natalia A Osna. Biomolecules. 2021 Oct;11:1497. PubMed: 34680130 PMC: PMC8533635