Immunohistochemistry of paraffin-embedded human colon cancer using UFM1 Antibody at dilution of 1:100

UFM1 Antibody

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C500000-50

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Description: UFM1 antibody LS-C500000 is an unconjugated rabbit polyclonal antibody to human UFM1. Validated for ELISA and IHC.
Application: ELISA, IHC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: BM-002 | C13orf20 | BA131P10.1 | Ubiquitin-fold modifier 1 | UFM1
UniProt Number: P61960
NCBI GenBank: NM_016617 | NP_057701.1
SwissProt: P61960

Target: Human UFM1
Antigen Species: Human
Epitope: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable).
Gene Name: UFM1