Formalin-fixed, paraffin-embedded human Basal Cell Carcinoma stained with TYRP1 Recombinant Rabbit Monoclonal Antibody (TYRP1/2340R).
TYRP1 / gp75 Antibody (aa 257-377, clone TYRP1/2340R)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751408-20
Catalog Number: LS-C751408
For bulk orders or custom formulations:
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- Description
- Gp75 antibody LS-C751408 is an unconjugated rabbit recombinant monoclonal antibody to human gp75 (TYRP1) (aa 257-377). Validated for ELISA and IHC.
- Application
- ELISA, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- B-PROTEIN | CAS2 | CATB | Glycoprotein 75 | Hstyrrp | gp75 | OCA3 | SHEP11 | TYRP1 | TRP-1 | Tyrosinase-related protein 1 | TYRP | TYRRP | Catalase B | DHICA oxidase | Melanoma antigen gp75
- Recommended Dilution: ELISA
- 2 - 4 ug/ml
- Recommended Dilution: IHC-P
- 1 - 2 µg/ml
- UniProt Number
- P17643
- NCBI GenBank
- NM_000550 | NP_000541.1
- SwissProt
- P17643
Target
- Target
- Human TYRP1 / gp75
- Antigen Species
- Human
- Epitope
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
- Gene Name
- TYRP1
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- TYRP1/2340R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant fragment of human TYRP1 protein (around aa 257-377). Antigen Molecular Weight: 75 kDa
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS