TREM2 / TREM-2 Antibody (clone 78.18, Low Endotoxin)

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Antibody:	Rat Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry (general)
Reactivity:	Mouse
Format:	Liquid

$654.00each

Catalog Number: LS-C188610-0.5

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Description: TREM-2 antibody LS-C188610 is an unconjugated rat monoclonal antibody to mouse TREM-2 (TREM2). Validated for Flow.
Application: FC, IHC
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: Trem2b | TREM-2 | TREM2 | Trem2a | Trem2c
Recommended Dilution: FC: 1:25 - 1:200
UniProt Number: Q9NZC2
NCBI GenBank: NM_018965 | NP_061838.1
SwissProt: Q9NZC2

Target: Mouse TREM2 / TREM-2
Antigen Species: Mouse
Epitope: Recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.
Gene Name: TREM2

Storage Conditions: Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS

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