TREM1 Antibody (clone L5-B8.2A12.3A12)

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Antibody:	Rat Monoclonal
Applications:	Flow Cytometry, Immunofluorescence, Immunohistochemistry, Frozen, Western Blot
Reactivity:	Mouse
Format:	Liquid

$392.00each

Catalog Number: LS-C188343-0.25

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Description: TREM1 antibody LS-C188343 is an unconjugated rat monoclonal antibody to mouse TREM1. Validated for Flow, IF, IHC and WB.
Application: FC, IF, IHC-F, WB
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD354 | CD354 antigen | Triggering-receptor TREM1 | TREM-1 | TREM1
Recommended Dilution: FC: 1:25 - 1:100
UniProt Number: Q9NP99
NCBI GenBank: NM_018643 | NP_061113.1
SwissProt: Q9NP99

Target: Mouse TREM1
Antigen Species: Mouse
Epitope: Recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.
Gene Name: TREM1

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS