TPO / Thyroid Peroxidase Antibody (clone MoAb47)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Monoclonal
Applications:	Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

$320.00each

Catalog Number: LS-C95596-0.1

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Description: Thyroid Peroxidase antibody LS-C95596 is an unconjugated mouse monoclonal antibody to human Thyroid Peroxidase (TPO). Validated for IHC.
Application: IHC, IHC-P
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: MSA | Thyroid microsomal antigen | Thyroid peroxidase | TPO | TDH2A | TPX | Thyroperoxidase
Recommended Dilution: IHC-P: 1:10 - 1:25
UniProt Number: P07202
NCBI GenBank: NM_000547 | NP_000538.3
SwissProt: P07202

Target: Human TPO / Thyroid Peroxidase
Antigen Species: Human
Epitope: Thyroid Peroxidase (TPO) is a transmembrane protein of 107kD containing a heme prosthetic group and it is present as dimmer on the apical surface of the thyroid follicular cells. TPO is the primary enzyme involved in thyroid hormone synthesis. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. may be useful aid in the differentiation between the benign and malignant thyroid tumors.
Gene Name: TPO

Immunogen: Human Thyroid Peroxidase (hTPO) purified from thyroid microsomes by immunoaffinity chromatography.
Immunogen Type: Tissue Extract

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