Formalin-fixed, paraffin-embedded human Pancreas stained with Topo I Rabbit Recombinant Monoclonal Antibody (TOP1MT/2883R).

TOP1MT Antibody (clone TOP1MT/2883R)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Recombinant Monoclonal
Applications:	Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

$379.00each

Catalog Number: LS-C751104-20

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Description: TOP1MT antibody LS-C751104 is an unconjugated rabbit recombinant monoclonal antibody to human TOP1MT. Validated for IHC.
Application: IHC-P
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: TOP1MT | Mitochondrial topoisomerase IB
Recommended Dilution: IHC-P: 0.5 - 1 µg/ml
UniProt Number: Q969P6
SwissProt: Q969P6

Target: Human TOP1MT
Antigen Species: Human
Epitope: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
Gene Name: TOP1MT