Immunohistochemistry of paraffin-embedded human glioma cancer using TOLLIP Antibody at dilution of 1:100

TOLLIP Antibody

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C501870-50

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Description: TOLLIP antibody LS-C501870 is an unconjugated rabbit polyclonal antibody to human TOLLIP. Validated for ELISA and IHC.
Application: ELISA, IHC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: Adapter protein | IL-1RAcPIP | Toll interacting protein | Toll-interacting protein | TOLLIP
UniProt Number: Q9H0E2
NCBI GenBank: NM_019009 | NP_061882.2
SwissProt: Q9H0E2

Target: Human TOLLIP
Antigen Species: Human
Epitope: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Gene Name: TOLLIP