TNFSF10 / TRAIL Antibody (aa95-281, clone 2E5, Low Endotoxin)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$865.00each
Catalog Number: LS-C188227-0.5
Catalog Number: LS-C188227
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- Description
- TRAIL antibody LS-C188227 is an unconjugated mouse monoclonal antibody to human TRAIL (TNFSF10) (aa95-281). Validated for Flow and WB.
- Application
- FC, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Apo-2L | APO2L | Apo-2 ligand | CD253 | CD253 antigen | TNFSF10 | TRAIL | Protein TRAIL | TL2
- UniProt Number
- P50591
- NCBI GenBank
- NM_003810 | NP_003801.1
- SwissProt
- P50591
Target
- Target
- Human TNFSF10 / TRAIL
- Antigen Species
- Human
- Epitope
- TRAIL is a cytotoxic protein closely related to Fas (CD95), which induces extensive apoptosis in a range of cell types. TRAIL induces apoptosis via the receptors DR4 and DR5. Most normal tissues are resistant to TRAIL induced apoptosis due to their expression of decoy receptors, DcR1 and DcR2, which antagonize TRAIL activity. TRAIL is expressed by cell lines, activated lymphocytes and on syncytiotrophoblast cells in first trimester pregnancy. Neutralizes TRAIL activity.
- Gene Name
- TNFSF10
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 2E5
- Isotype
- IgG1
Immunogen
- Immunogen
- Recombinant human CD253 (TRAIL) aa 95-281
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS