Immunofluorescent staining of CaCo-2 cells with Rabbit anti-Human CD120b , green. Counterstained with actin, red and nuclei, blue. This image was taken for the unconjugated form of this product. Other forms have not been tested.
TNFRSF1B / TNFR2 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Western Blot |
| Reactivity: | Human |
| Format: | Lyophilized |
$523.00each
Catalog Number: LS-C187866-0.1
Catalog Number: LS-C187866
For bulk orders or custom formulations:
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- Description
- TNFR2 antibody LS-C187866 is an unconjugated rabbit polyclonal antibody to human TNFR2 (TNFRSF1B). Validated for ELISA, IF and WB.
- Application
- ELISA, IF, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- CD120b antigen | CD120b | p75 TNF receptor | Soluble TNFR1B variant 1 | TNFBR | Tumor necrosis factor receptor | TNF-R-II | TNF-R75 | TNFR2 | p75TNFR | p80 TNF-alpha receptor | TBPII | TNF-R2 | TNFR80 | TNFRSF1B | TNF-RII | TNFR-II | TNFR1B
- Recommended Dilution: ELISA
- 0.5 - 2 ug/ml
- UniProt Number
- P20333
- NCBI GenBank
- NM_001066 | NP_001057.1
- SwissProt
- P20333
Target
- Target
- Human TNFRSF1B / TNFR2
- Antigen Species
- Human
- Epitope
- Recognizes the soluble form of human CD120b, otherwise known as sTNF receptor type II (sTNFR1I), a member of the tumor necrosis factor receptor (TNFR) superfamily, produced by proteolytic cleavage of the membrane form by the metalloprotease TACE. CD120b plays a key role in regulating the inflammatory response, acting as a receptor for both tumor necrosis factor alpha (TNF-alpha) and TNF-beta, and is also involved in programmed cell death and anti-viral activity. sTNFR1I acts as an inhibitor of TNF-alpha induced responses, by acting as a decoy receptor.
- Gene Name
- TNFRSF1B
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- (PHP215).
Format
- Conjugate/Label
- Unconjugated
- Format
- Lyophilized
- Formulation
- PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Before reconstitution store at 4°C. After reconstitution store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS