Human peripheral blood lymphocytes stained with purified 122, followed by biotinylated anti-mouse IgG and Sav-PE
TNFRSF14 / CD270 / HVEM Antibody (clone 122)
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
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- Description
- HVEM antibody LS-C41150 is an unconjugated mouse monoclonal antibody to human HVEM (TNFRSF14 / CD270). Validated for ELISA, Flow and WB. Cited in 3 publications.
- Application
- ELISA, FC, IHC, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD270 | CD270 antigen | CD40-like protein | Herpesvirus entry mediator | Herpesvirus entry mediator A | HVEM | LIGHTR | Herpes virus entry mediator A | TR2 | ATAR | HVEA | TNFRSF14
- UniProt Number
- Q92956
- NCBI GenBank
- NM_003820 | NP_003811.2
- SwissProt
- Q92956
Target
- Target
- Human TNFRSF14 / CD270 / HVEM
- Antigen Species
- Human
- Epitope
- Recombinant human HVEM protein.
- Gene Name
- TNFRSF14
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 122
- Isotype
- IgG1
Immunogen
- Immunogen
- Recombinant human TNFRSF14.
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
- Concentration
- 0.5 mg/mL
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Recommended Storage Buffer
- Phosphate-buffered
Polymorphic variants of LIGHT (TNF superfamily-14) alter receptor avidity and bioavailability. Cheung TC, Coppieters K, Sanjo H, Oborne LM, Norris PS, Coddington A, Granger SW, Elewaut D, Ware CF. Journal of immunology (Baltimore, Md. : 1950). 2010;185:1949-58.
PubMed: 20592286 · PMC: PMC2921593
B and T lymphocyte attenuator mediates inhibition of tumor-reactive CD8+ T cells in patients after allogeneic stem cell transplantation. Hobo W, Norde WJ, Schaap N, Fredrix H, Maas F, Schellens K, Falkenburg JH, Korman AJ, Olive D, van der Voort R, Dolstra H. Journal of immunology (Baltimore, Md. : 1950). 2012;189:39-49.
PubMed: 22634623
Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer. Ramsay AG, Clear AJ, Fatah R, Gribben JG. Blood. 2012;120:1412-21.
PubMed: 22547582 · PMC: PMC3423779