TNFRSF12A / TWEAK Receptor Antibody (clone ITEM-4)

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Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Western Blot
Reactivity:	Human
Format:	Liquid

$392.00each

Catalog Number: LS-C188542-0.2

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Description: TWEAK Receptor antibody LS-C188542 is an unconjugated mouse monoclonal antibody to human TWEAK Receptor (TNFRSF12A). Validated for Flow, IHC and WB.
Application: FC, IHC, IHC-F, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD266 antigen | CD266 | FGF-inducible 14 | TNFRSF12A | FN14 | Tweak-receptor | TWEAKR
Recommended Dilution: FC: 1:25 - 1:200
UniProt Number: Q9NP84
NCBI GenBank: NM_016639 | NP_057723.1
SwissProt: Q9NP84

Target: Human TNFRSF12A / TWEAK Receptor
Antigen Species: Human
Epitope: Recognizes human CD266, otherwise known as Fn14/TWEAK Receptor, a 14kD type I transmembrane glycoprotein and member of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, including the heart, lung and kidney, and at elevated levels by human brain and liver tumors. The interaction between CD266 and its ligand CD255 (TWEAK), induces the proliferation and migration of endothelial cells and also angiogenesis, and studies have shown that CD255-induced apoptosis of some tumor cell lines is mediated by CD266. Clone ITEM-4 is cross-reactive with mouse CD266, and also with Rat-1 cells in flow cytometry.
Gene Name: TNFRSF12A

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS

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