Western blot of extracts (10ug) from 4 different cell lines and 1 human tissue by using anti-TNFRSF10B monoclonal antibody at 1:200 dilution.
TNFRSF10B / Killer / DR5 Antibody (aa203-411, clone OTI1B9)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$443.00each
Catalog Number: LS-C340229-100
Catalog Number: LS-C340229
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- Description
- DR5 antibody LS-C340229 is an unconjugated mouse monoclonal antibody to human DR5 (TNFRSF10B / Killer) (aa203-411). Validated for IHC and WB. Cited in 1 publication.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Cytotoxic TRAIL receptor-2 | CD262 antigen | DR5 | Death receptor 5 | KILLER | TRAIL-R2 | TRICK2B | TNFRSF10B | TRAILR2 | TRICK2A | TRICKB | TRICK2 | CD262 | Fas-like protein | TRAIL receptor 2 | ZTNFR9
- Recommended Dilution: IHC-P
- 1:150
- UniProt Number
- O14763|Q6FH58
- NCBI GenBank
- NM_147187
- SwissProt
- O14763
Target
- Target
- Human TNFRSF10B / Killer / DR5
- Antigen Species
- Human
- Epitope
- Human TNFRSF10B / DR5
- Gene Name
- TNFRSF10B
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- OTI1B9
- Isotype
- IgG1
Immunogen
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 203-411 of human TNFRSF10B(NP_671716) produced in E. coli.
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
- Concentration
- 1 mg/mL
- Volume
- 100 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Multimeric Anti-DR5 IgM Agonist Antibody IGM-8444 Is a Potent Inducer of Cancer Cell Apoptosis and Synergizes with Chemotherapy and BCL-2 Inhibitor ABT-199. Beatrice T Wang, Tasnim Kothambawala #, Ling Wang #, Thomas J Matthew #, Susan E Calhoun, Avneesh K Saini, Maya F Kotturi, Genevive Hernandez, Eric W Humke, Marvin S Peterson, Angus M Sinclair, Bruce A Keyt. The Breast : official journal of the European Society of Mastology. 2021 Dec;;20:2483-2494. PubMed: 34711645