LSBio
TLR3 Antibody (clone 40C1285.6)

Western blot of TLR3 in lysates from untransfected 293 cells (lane A), 293 cells transfected with human TLR3 cDNA (lane B), and 20 ug/lane human intestine tissue lysate (lane C).

TLR3 Antibody (clone 40C1285.6)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Goat, Human, Non-Human Primate, Sheep
Format:Liquid
See all Human TLR3 antibodies →
$394.00each
Catalog Number: LS-C545-0.1

For bulk orders or custom formulations:

Request a Quote

Overview

Description
TLR3 antibody LS-C545 is an unconjugated mouse monoclonal antibody to TLR3 from human. It is reactive with human, goat, monkey and other species. Validated for Flow, IHC, IP and WB. Cited in 3 publications.
Application
FC, IHC, IHC-P, IP, WB
Reactivity
Gt, Hu, NHP, Sh
Predicted Reactivity
Bovine, Dog, Guinea Pig, Pig
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD283 | Toll-like receptor 3 | TLR3 | CD283 antigen | IIAE2
Recommended Dilution: WB
1 - 3 µg/ml
UniProt Number
O15455
SwissProt
O15455

Target

Target
Human TLR3
Antigen Species
Human
Epitope
KLH-conjugated synthetic peptide of human TLR3.
Gene Name
TLR3

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
40C1285.6
Isotype
IgG1

Immunogen

Immunogen
A synthetic peptide corresponding to amino acids 55-70 (VLNLTHNQLRRLPAAN)of human TLR3 was used as immunogen, Gen Bank no. gb|AAH59372.1|. Human TLR3 is an 870 amino acid protein. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Ferret, Sheep, Goat (100%); Chimpanzee, Dog, Bovine, Panda, Pig, Zebu, Guinea pig (94%); Mouse, Rat, Cat, Bat, Elephant (88%); Horse, Rabbit, Opossum (81%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.05% Sodium Azide
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

A comparison of the impact of Shimen and C strains of classical swine fever virus on Toll-like receptor expression. Cao Z, Guo K, Zheng M, Ning P, Li H, Kang K, Lin Z, Zhang C, Liang W, Zhang Y. The Journal of general virology. 2015;96:1732-45.

PubMed: 25805409


Tissue expression of Toll-like receptors 2, 3, 4 and 7 in swine in response to the Shimen strain of classical swine fever virus. Cao Z, Zheng M, Lv H, Guo K, Zhang Y. Molecular medicine reports. 2018 May;17:7122-7130.

PubMed: 29568891 · PMC: PMC5928672


Ontogeny of white matter, toll-like receptor expression, and motor skills in the neonatal ferret. Snyder JM, Wood TR, Corry K, Moralejo DH, Parikh P, Juul SE. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2018 November;70:25-33.

PubMed: 29791868 · PMC: PMC6195435

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.