Mouse spleen cells stained with Rat anti-Mouse CD8 alpha:APC and (A) Rat anti-Mouse CD283 or (B) rat IgG control. Detection with Goat anti-Rat IgG:Dylight488 was performed following permeabilization of the cells with Leucoperm prior to incubation with Rat anti-Mouse CD283. This image was taken for the unconjugated form of this product. Other forms have not been tested.

TLR3 Antibody (clone 11F8)

Primary AntibodyLSBio Guarantee

Antibody:	Rat Monoclonal
Applications:	Flow Cytometry, Immunofluorescence
Reactivity:	Mouse
Format:	Liquid

$286.00each

Catalog Number: LS-C187581-0.1

Unit Size

Quantity

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Overview

Description: TLR3 antibody LS-C187581 is an unconjugated rat monoclonal antibody to mouse TLR3. Validated for Flow and IF.
Application: FC, IF
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD283 | Toll-like receptor 3 | TLR3 | CD283 antigen | IIAE2
UniProt Number: O15455
NCBI GenBank: NM_003265 | NP_003256.1
SwissProt: O15455

Target

Target: Mouse TLR3
Antigen Species: Mouse
Epitope: Clone 11F8 recognizes Mouse TLR3, otherwise known as CD283. TLR3 is a member of the Toll-like receptor (TLR) family and functions as a receptor for double-stranded (ds) RNA. TLRs are expressed on the cell surface and in the endocytic compartment with the purpose of recognizing pathogen-associated molecular patterns (PAMPs) expressed on infectious agents. In addition TLR's initiate cell signalling to induce production of cytokines necessary for the innate immunity and subsequent adaptive immunity. TLR3 is expressed by dendritic cells and B lymphocytes.
Gene Name: TLR3

Antibody

Host Species: Rat
Clonality: Monoclonal
Clone: 11F8
Isotype: IgG2a

Format

Conjugate/Label: Unconjugated
Format: Liquid
Formulation: PBS, 0.09% Sodium Azide
Concentration: 1 mg/mL
Preservative: Yes
Purification Method: Protein G Affinity

Storage & Handling

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS