Formalin-fixed, paraffin-embedded Human Endometrial Carcinoma stained with TLE1 Rabbit Recombinant Monoclonal Antibody (TLE1/2946R).
TLE1 / TLE 1 Antibody (aa 175-338, clone TLE1/2946R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751396-100
Catalog Number: LS-C751396
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- Description
- TLE 1 antibody LS-C751396 is an unconjugated rabbit recombinant monoclonal antibody to human TLE 1 (TLE1) (aa 175-338). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- E(Sp1) homolog | ESG | GRG1 | TLE1 | Enhancer of split groucho 1 | ESG1
- Recommended Dilution: IHC-P
- 1 - 2 µg/ml
- UniProt Number
- Q04724
- NCBI GenBank
- NM_005077 | NP_005068.2
- SwissProt
- Q04724
Target
- Target
- Human TLE1 / TLE 1
- Antigen Species
- Human
- Epitope
- Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.
- Gene Name
- TLE1
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- TLE1/2946R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant human TLE1 fragment (aa 175-338). Antigen Molecular Weight: 83 kDa
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS