LSBio
TIMP2 Antibody (N-Terminus, clone 3A4)

Formalin-fixed, paraffin-embedded testis stained with TIMP-2 antibody.

TIMP2 Antibody (N-Terminus, clone 3A4)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry (general), Western Blot
Reactivity:Bovine, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat
Format:Liquid
See all Human TIMP2 antibodies →
$299.00each
Catalog Number: LS-C95516-0.1

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Overview

Description
TIMP2 antibody LS-C95516 is an unconjugated mouse monoclonal antibody to TIMP2 (N-Terminus) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB.
Application
IHC, WB
Reactivity
Bov, GP, Hu, Ms, Por, Rb, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
TIMP2 | Metalloproteinase inhibitor 2 | TIMP-2 | CSC-21K
UniProt Number
P16035
SwissProt
P16035

Target

Target
Human TIMP2
Antigen Species
Human
Epitope
Is specific to 21 kD protein known as TIMP-2. TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family. TIMPs are of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kD Type IV collagenase (MMP-2) and active form of 92 kD Type IV collagenase (MMP-9). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. This antibody cross reacts with mouse, rat, rabbit, cow and Guinea pig.
Gene Name
TIMP2

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
3A4
Isotype
IgG2a
Light Chain
Kappa Light Chain
Origin Species
Human

Immunogen

Immunogen
BALB/C mice were injected with a synthetic peptide from the N-Terminus of human TIMP-2.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
0.05% Sodium Azide
Volume
0.1 Milliliter
Preservative
Yes

Storage & Handling

Storage Conditions
Store at 2°C to 8°C. Do not freeze.

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