
TACR3 / NK3R Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$463.00each
Catalog Number: LS-C56946-0.1
Catalog Number: LS-C56946
For bulk orders or custom formulations:
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- Description
- NK3R antibody LS-C56946 is an unconjugated rabbit polyclonal antibody to human NK3R (TACR3). Validated for IHC and WB.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- HH11 | Nmk-r | NK3R | NKR | TACR3 | Tachykinin receptor 3 | Neurokinin B | Neurokinin B receptor | NK-3 receptor | NK-3R | TAC3R | Neurokinin 3 receptor | Neurokinin beta receptor | Neuromedin-K receptor | TAC3RL
- Recommended Dilution: IHC-P
- 5 µg/ml
- Recommended Dilution: WB
- 0.5 - 1 µg/ml
- UniProt Number
- P29371
- NCBI GenBank
- NM_001059 | NP_001050.1
- SwissProt
- P29371
Target
- Target
- Human TACR3 / NK3R
- Antigen Species
- Human
- Epitope
- Recognizes human TACR3 otherwise known as NK3 Receptor (NK3R), a 52.2 kD multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. TACR3 is a receptor for the tachykinin neuropeptide, neuromedin-k otherwise known as neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system, and it is likely that these signals lead to the release of vasopressin and oxytocin into the circulation. Studies with mice indicate that TACR3 is involved in learning and memory. AHP1492 does not recognize NK1R or NK2R.
- Gene Name
- TACR3
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- An 18 amino acid peptide near the centre of human TACR3.
- Immunogen Type
- Peptide
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.02% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS
