Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
SRSF6 / SRP55 Antibody (aa143-192)
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- SRP55 antibody LS-B5712 is an unconjugated rabbit polyclonal antibody to human SRP55 (SRSF6) (aa143-192). Validated for IHC and WB. Cited in 2 publications.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- B52 | Pre-mRNA-splicing factor SRP55 | SFRS6 | SRSF6 | SR splicing factor 6 | SRP55
- Recommended Dilution: IHC-P
- 5 µg/ml
- UniProt Number
- Q13247
- NCBI GenBank
- NM_006275 | NP_006266.2
- SwissProt
- Q13247
Target
- Target
- SRSF6 / SRP55
- Antigen Species
- Human
- Specificity
- Human SRSF6 / SFRS6
- Epitope
- Human SRSF6 / SFRS6
- Gene Name
- SRSF6
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide located between aa143-192 of human SRSF6 (Q13247, NP_006266). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Bat, Rabbit, Horse, Pig, Opossum (100%); Turkey, Zebra finch, Chicken, Platypus (85%); Stickleback, Zebrafish (84%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% sodium azide, 2% sucrose
- Concentration
- 0.5 mg/mL
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
- Recommended Storage Buffer
- PBS
Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease. Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, Bondulich MK, Smith DL, Faull RL, Roos RA, Howland D, Detloff PJ, Housman DE, Bates GP. Proceedings of the National Academy of Sciences of the United States of America. 2013;110:2366-70.
PubMed: 23341618 · PMC: PMC3568346
Huntington's disease is a four-repeat tauopathy with tau nuclear rods. Fern[Character e1]ndez-Nogales M, Cabrera JR, Santos-Galindo M, Hoozemans JJ, Ferrer I, Rozemuller AJ, Hern[Character e1]ndez F, Avila J, Lucas JJ. Nature medicine. Aug;20:881-5.
PubMed: 25038828