SNCA / Alpha-Synuclein Antibody (phospho-S129)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$301.00each
Catalog Number: LS-C380861-50
Catalog Number: LS-C380861
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- Description
- Alpha-Synuclein antibody LS-C380861 is an unconjugated rabbit polyclonal antibody to Alpha-Synuclein (SNCA) (pS129) from human. It is reactive with human, mouse and rat. Validated for ELISA, IHC and WB. Cited in 2 publications.
- Application
- ELISA, IHC, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Alpha-synuclein | PARK4 | PD1 | SNCA | Synuclein alpha-140 | NACP | PARK1 | aSynuclein | a-Synuclein
- Recommended Dilution: ELISA
- 1:5000
- Recommended Dilution: IHC
- 1:100 - 1:300
- Recommended Dilution: WB
- 1:500 - 1:2000
- UniProt Number
- P37840
- NCBI GenBank
- NM_000345 | NP_000336.1
- SwissProt
- P37840
Target
- Target
- Human SNCA / Alpha-Synuclein
- Antigen Species
- Human
- Epitope
- Phospho-Synuclein-alpha (S129) Polyclonal Antibody detects endogenous levels of Synuclein-alpha protein only when phosphorylated at S129.
- Gene Name
- SNCA
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Synthesized peptide derived from human Synuclein-alpha around the phosphorylation site of S129.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.02% Sodium Azide, 50% Glycerol, 0.5% BSA
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Netrin-1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson's disease features. Mélissa Jasmin, Eun Hee Ahn, Merja H Voutilainen, Joanna Fombonne, Catherine Guix, Tuulikki Viljakainen, Seong Su Kang, Li-Ying Yu, Mart Saarma, Patrick Mehlen, Keqiang Ye. The EMBO journal. 2021 February;40:e105537.
PubMed: 33351190 · PMC: PMC7849168
UNC5C Receptor Proteolytic Cleavage by Active AEP Promotes Dopaminergic Neuronal Degeneration in Parkinson's Disease. Guiqin Chen, Eun Hee Ahn, Seong Su Kang, Yiyuan Xia, Xia Liu, Zhaohui Zhang, Keqiang Ye. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2022 March;9:e2103396.
PubMed: 35023303 · PMC: PMC8895126