Anti-SNAI2 / SLUG antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
SNAI2 / SLUG Antibody (aa92-141)
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
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- Description
- SLUG antibody LS-B5598 is an unconjugated rabbit polyclonal antibody to human SLUG (SNAI2) (aa92-141). Validated for IHC and WB. Cited in 3 publications.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- SLUG | SLUGH1 | Snail homolog 2 (Drosophila) | SNAIL2 | SLUGH | Protein snail homolog 2 | WS2D | SNAI2 | Zinc finger protein SNAI2
- Recommended Dilution: IHC-P
- 5 µg/ml
- Recommended Dilution: WB
- 0.2 - 1 µg/ml
- UniProt Number
- O43623
- NCBI GenBank
- NM_003068 | NP_003059.1
- SwissProt
- O43623
Target
- Target
- SNAI2 / SLUG
- Antigen Species
- Human
- Specificity
- Human SNAI2 / SLUG
- Epitope
- Human SNAI2 / SLUG
- Gene Name
- SNAI2
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide located between aa92-141 of human SNAI2 (O43623, NP_003059). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Sheep, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig, Turkey, Zebra finch, Chicken (100%); Mouse, Rat, Hamster, Opossum (92%); Platypus, Xenopus (85%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% sodium azide, 2% sucrose
- Volume
- 100 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
- Recommended Storage Buffer
- PBS
An in vitro model that recapitulates the epithelial to mesenchymal transition (EMT) in human breast cancer. Katz E, Dubois-Marshall S, Sims AH, Gautier P, Caldwell H, Meehan RR, Harrison DJ. PloS one. 2011;6:e17083.
PubMed: 21347235 · PMC: PMC3039655
The use of automated quantitative analysis to evaluate epithelial-to-mesenchymal transition associated proteins in clear cell renal cell carcinoma. O'Mahony FC, Faratian D, Varley J, Nanda J, Theodoulou M, Riddick AC, Harrison DJ, Stewart GD. PloS one. 2012;7:e31557.
PubMed: 22363672 · PMC: PMC3283650
Two possible mechanisms of epithelial to mesenchymal transition in invasive ductal breast cancer. Dubois-Marshall S, Thomas JS, Faratian D, Harrison DJ, Katz E. Clinical & experimental metastasis. 2011 Dec;28:811-8.
PubMed: 21789718