Immunohistochemistry of paraffin-embedded human kidney tissue using SMURF1 Antibody at dilution of 1:100

SMURF1 Antibody

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general)
Reactivity:	Human, Mouse
Format:	Liquid

$300.00each

Catalog Number: LS-C501878-50

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Description: SMURF1 antibody LS-C501878 is an unconjugated rabbit polyclonal antibody to SMURF1 from human. It is reactive with human and mouse. Validated for ELISA, IF and IHC.
Application: ELISA, IF, IHC
Reactivity: Hu, Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: E3 ubiquitin ligase SMURF1 | KIAA1625 | HSMURF1 | SMURF1
UniProt Number: Q9HCE7
NCBI GenBank: NP_851994.1
SwissProt: Q9HCE7

Target: Human SMURF1
Antigen Species: Human
Epitope: E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Gene Name: SMURF1