Western blot analysis of extracts of various cell lines, using SMPD1 antibody.
SMPD1 / Acid Sphingomyelinase Antibody (aa70-340)
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunofluorescence, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
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- Description
- Acid Sphingomyelinase antibody LS-C334919 is an unconjugated rabbit polyclonal antibody to Acid Sphingomyelinase (SMPD1) (aa70-340) from human. It is reactive with human, mouse and rat. Validated for IF and WB. Cited in 3 publications.
- Application
- IF, IHC, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Acid sphingomyelinase | ASM | SMPD1 | NPD | ASMASE
- Recommended Dilution: IF/ICC
- 1:10 - 1:100
- Recommended Dilution: WB
- 1:500 - 1:2000
- UniProt Number
- P17405
- NCBI GenBank
- NM_000543 | NP_000534.3
- SwissProt
- P17405
Target
- Target
- Human SMPD1 / Acid Sphingomyelinase
- Antigen Species
- Human
- Epitope
- Human SMPD1 / Acid Sphingomyelinase
- Gene Name
- SMPD1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant protein of human SMPD1
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol
- Volume
- 20 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Regulation of the amount of ceramide-1-phosphate synthesized in differentiated human podocytes. Shamroop Kumar Mallela, Alla Mitrofanova, Sandra Merscher, Alessia Fornoni. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2019 December;1864:158517.
PubMed: 31487557 · PMC: PMC6832884
Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases. Yue-Hong Chen, Rong-Han Liu, Ya-Zhou Cui, Aubryanna Hettinghouse, Wen-Yu Fu, Lei Zhang, Chen Zhang, Chuan-Ju Liu. Arthritis research & therapy. 2022 January;24:27.
PubMed: 35045889 · PMC: PMC8767691
Endothelial Acid Sphingomyelinase Promotes NLRP3 Inflammasome and Neointima Formation During Hypercholesterolemia. Xinxu Yuan, Owais M Bhat, Yao Zou, Xiang Li, Yang Zhang, Pin-Lan Li. Journal of lipid research. 2022 October;63:100298.
PubMed: 36252682 · PMC: PMC9672920