Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with SM-MHC Recombinant Rabbit Monoclonal Antibody (MYH11/2303R).
SMMHC / MYH11 Antibody (clone MYH11/2303R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751287-100
Catalog Number: LS-C751287
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- Description
- MYH11 antibody LS-C751287 is an unconjugated rabbit recombinant monoclonal antibody to human MYH11 (SMMHC). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- AAT4 | FAA4 | KIAA0866 | Myosin-11 | MYH11 | Myosin heavy chain 11 | SMHC | SMMHC
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P35749
- NCBI GenBank
- NM_002474 | NP_002465.1
- SwissProt
- P35749
Target
- Target
- Human SMMHC / MYH11
- Antigen Species
- Human
- Epitope
- Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
- Gene Name
- MYH11
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- MYH11/2303R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human MYH11 protein. Antigen Molecular Weight: 205 kDa (MHC-1) and 200 kDa (MHC-2)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS