LSBio
SLA Class II DR Antibody (clone 2E9/13)

Pig peripheral blood lymphocytes stained with Mouse anti-Pig SLA Class II DR followed by Goat anti-Mouse IgG:FITC. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SLA Class II DR Antibody (clone 2E9/13)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunohistochemistry, Frozen, Immunoprecipitation
Reactivity:Pig
Format:Liquid
See all Pig SLA Class II DR antibodies →
$363.00each
Catalog Number: LS-C187489-0.1

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Overview

Description
SLA Class II DR antibody LS-C187489 is an unconjugated mouse monoclonal antibody to pig SLA Class II DR. Validated for Flow, IHC and IP.
Application
FC, IHC-F, IP
Reactivity
Por
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies

Target

Target
Pig SLA Class II DR
Antigen Species
Pig
Epitope
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR. Clone 2E9/13 is specific for SLA DR molecules which are expressed on all B cells, antigen presenting cells and on certain subsets of resting and activated T cells. This clone reacts with lymphocytes from all outbred and miniature pigs so far tested, suggesting that it recognizes a monomorphic determinant of porcine SLA DR. Immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labeled porcine peripheral blood mononuclear cells. Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and Staphylococcal enterotoxin B, see for details.

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
2E9/13
Isotype
IgG2b

Immunogen

Immunogen
Porcine monocytes.
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.