LSBio
SIRT6 / Sirtuin 6 Antibody (aa56-105)

Anti-SIRT6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SIRT6 / Sirtuin 6 Antibody (aa56-105)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
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$470.00each
Catalog Number: LS-B5589-50

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Overview

Description
Sirtuin 6 antibody LS-B5589 is an unconjugated rabbit polyclonal antibody to Sirtuin 6 (SIRT6) (aa56-105) from human. It is reactive with human and mouse. Validated for IHC and WB. Cited in 3 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu, Ms
Intended Use
RUO
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
SIR2-like protein 6 | Sirtuin type 6 | SIR2L6 | Sir2-related protein type 6 | Sirtuin 6 | SIRT6
Recommended Dilution: IHC-P
10 µg/ml
Recommended Dilution: WB
1.25 µg/ml
UniProt Number
Q8N6T7
SwissProt
Q8N6T7

Target

Target
SIRT6 / Sirtuin 6
Antigen Species
Hu
Specificity
Human SIRT6
Epitope
Human SIRT6
Gene Name
SIRT6

Antibody

Host Species
Rb
Clonality
Polyclonal
Origin Species
Hu

Immunogen

Immunogen
Synthetic peptide located between aa56-105 of human SIRT6 (Q8N6T7, NP_057623). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Galago, Marmoset, Mouse, Hamster, Elephant, Dog, Bat, Pig, Opossum (100%); Gibbon, Rat, Bovine, Horse, Guinea pig, Platypus (92%); Turkey, Zebra finch, Chicken, Xenopus (84%).

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
PBS, 0.09% sodium azide, 2% sucrose
Concentration
1 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Prot A

Storage & Handling

Storage Conditions
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS
The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells. Choe M, Brusgard JL, Chumsri S, Bhandary L, Zhao XF, Lu S, Goloubeva OG, Polster BM, Fiskum GM, Girnun GD, Kim MS, Passaniti A. Journal of cellular biochemistry. 2015;116:2210-26. PubMed: 25808624 PMC: PMC4885214

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