SIRPA / CD172a Antibody (clone BL1H7)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot |
| Reactivity: | Pig |
| Format: | Liquid |
$304.00each
Catalog Number: LS-C187488-0.1
Catalog Number: LS-C187488
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- Description
- CD172a antibody LS-C187488 is an unconjugated mouse monoclonal antibody to pig CD172a (SIRPA). Validated for Flow, IHC, IP and WB.
- Application
- FC, IHC, IHC-F, IHC-P, IP, WB
- Reactivity
- Por
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD172A | CD172a antigen | Inhibitory receptors shps-1 | Inhibitory receptor SHPS-1 | Macrophage fusion receptor | MyD-1 antigen | p84 | SHPS-1 | SHPS1 | SIRP | Sirp-alpha-1 | Sirp-alpha-3 | Sirp-alpha1 | SIRPA | MYD1 | SIRPalpha | SIRPalpha2 | BIT | MFR | MYD-1 | PTPNS1 | SHP substrate 1 | Sirp-alpha-2 | CD172
- UniProt Number
- P78324
- NCBI GenBank
- NM_080792 | NP_542970.1
- SwissProt
- P78324
Target
- Target
- Pig SIRPA / CD172a
- Antigen Species
- Pig
- Epitope
- Porcine CD172a, a member of the signal regulatory protein (SIRP) family. Clone BL1H7 was originally clustered as SWC3 at the Third International Swine Cluster of Differentiation Workshop (;). CD172a is expressed on monocyte derived dendritic cells (MoDCs) also conventional (cDCs), plasmacytoid (pDCs) DCs and blood DCs.(; ). Clone BL1H7 immunoprecipitated a single band of ~90-110kD from preparations of biotinylated alveolar macrophages, a result confirmed by Western blotting analysis of alveolar macrophage lysates under non reducing conditions. Has proved a useful and reliable tool for immunohistochemical analysis of routinely processed, formalin fixed, paraffin embedded porcine tissues. Aberrant expression of CD172a has been noted on porcine leukemias with blast cells co-expressing lymphocytic markers CD5 and CD25 whilst expressing the Myeloid marker CD172a in a as opposed to the more characteristic of CD172+ cells seen in normal blood PBMC.
- Gene Name
- SIRPA
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- BL1H7
- Isotype
- IgG1
Immunogen
- Immunogen
- Porcine alveolar macrophages.
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS