Immunohistochemistry of formalin-fixed human breast invasive ductal carcinoma stained with Rabbit anti-human PAI-1 following heat mediated antigen retrieval using sodium citrate buffer (pH6.0). This image was taken for the unconjugated form of this product. Other forms have not been tested.
SERPINE1 / PAI-1 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Lyophilized |
$523.00each
Catalog Number: LS-C187761-0.1
Catalog Number: LS-C187761
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- Description
- PAI-1 antibody LS-C187761 is an unconjugated rabbit polyclonal antibody to human PAI-1 (SERPINE1). Validated for ELISA, IHC and WB.
- Application
- ELISA, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- PAI1 | PLANH1 | SERPINE1 | PAI-1 | Serpin E1
- Recommended Dilution: ELISA
- 0.5 - 2 ug/ml
- UniProt Number
- P05121
- NCBI GenBank
- NM_000602 | NP_000593.1
- SwissProt
- P05121
Target
- Target
- Human SERPINE1 / PAI-1
- Antigen Species
- Human
- Epitope
- Specifically recognizes human PAI-1 (plasminogen activator inhibitor-1), otherwise known as SERPINE1, a 45kD serine protease inhibitor and member of the serpin family, which acts as the primary inhibitor of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), and hence fibrinolysis. Increased levels of PAI-1 are associated with diabetes, cardiovascular disease and an increased occurrence of thrombosis in obesity, and can be induced by obesity related factors including insulin, glucose and VLDL (very-low-density lipoprotein).
- Gene Name
- SERPINE1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human PAI-1.
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Lyophilized
- Formulation
- PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Before reconstitution store at 4°C. After reconstitution store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS