LSBio
SARS-CoV-2 Spike Glycoprotein Antibody (aa318-510, clone CR3022)

SARS-CoV-2 Spike Glycoprotein Antibody (aa318-510, clone CR3022)

Primary AntibodyLSBio Guarantee
Antibody:Human Recombinant Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay
Reactivity:Virus / Viral Antigen
Format:Liquid
See all SARS-CoV-2 Spike Glycoprotein Human Recombinant Monoclonal (aa318-510) (CR3022) Antibody antibodies →
$551.00each
Catalog Number: LS-C829135-0.2

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Overview

Description
SARS-CoV-2 Spike Glycoprotein antibody LS-C829135 is an unconjugated human recombinant monoclonal antibody to SARS-CoV-2 Spike Glycoprotein (aa318-510) from coronavirus sars-cov and coronavirus sars-cov-2. Validated for ELISA.
Application
ELISA
Reactivity
Vir
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
SARS-CoV-2 | SARS-Cov2 | COVID-19 | SARS-CoV2 (COVID-19) Spike

Target

Target
SARS-CoV-2 Spike Glycoprotein Human Recombinant Monoclonal (aa318-510) (CR3022) Antibody
Epitope
LS-C829135 is a human IgG kappa recombinant form of a human IgG1 monoclonal antibody generated by sequencing peripheral blood lymphocytes of a patient exposed to the SARS-CoV (B-cell clone CR3022). This antibody binds to amino acids 318-510 in the S1 domain of the SARS-CoV and SARS-CoV-2 (COVID-19) Spike protein, as well as the P462L-substituted S318-510 fragments of the SARS spike protein. The binding epitope is only accessible in the "open" conformation of the spike protein. Detailed information about antibody binding can be found in these publications: (SARS-CoV-2) Tian X et al. Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody. Emerg Microbes Infect. 2020 Feb 17;9(1):382-385. PMID: 32065055(SARS-CoV) ter Meulen et al. Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants PLoS Med. 2006 Jul; 3(7): e237 PMID:16796401.An alternate Rabbit IgG kappa recombinant version of this antibody is also available as LS-C829136.

Antibody

Host Species
Human
Clonality
Recombinant Monoclonal
Clone
CR3022
Isotype
IgG1
Light Chain
Kappa Light Chain

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.02% ProClin™ 300.
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.