LSBio
SAMD8 Antibody

Immunohistochemistry of paraffin-embedded human lymph node tissue using SAMD8 Antibody at dilution of 1:100

SAMD8 Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all Human SAMD8 antibodies →
$300.00each
Catalog Number: LS-C501330-50

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Overview

Description
SAMD8 antibody LS-C501330 is an unconjugated rabbit polyclonal antibody to human SAMD8. Validated for ELISA and IHC.
Application
ELISA, IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
SAMD8 | Sphingomyelin synthase related | SMSr
UniProt Number
Q96LT4
SwissProt
Q96LT4

Target

Target
Human SAMD8
Antigen Species
Human
Epitope
Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.
Gene Name
SAMD8

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Sphingomyelin synthase-related protein 1 protein (1-152AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.