Formalin-fixed, paraffin-embedded human Melanoma stained with S100B Rabbit Recombinant Monoclonal Antibody (S100B/1706R).
S100B / S100 Beta Antibody (clone S100B/1706R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751354-100
Catalog Number: LS-C751354
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- Description
- S100 Beta antibody LS-C751354 is an unconjugated rabbit recombinant monoclonal antibody to human S100 Beta (S100B). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- NEF | S100B | Protein S100-B | S100 | S100 calcium binding protein B | S100 calcium-binding protein B | S100beta | S-100 protein beta chain | S-100 protein subunit beta | S100-B
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P04271
- NCBI GenBank
- NM_006272 | NP_006263.1
- SwissProt
- P04271
Target
- Target
- Human S100B / S100 Beta
- Antigen Species
- Human
- Epitope
- S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
- Gene Name
- S100B
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- S100B/1706R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human S100B protein. Antigen Molecular Weight: 10-12 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, no preservatives.
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Short term: store at -20°C. Long term: store at -80°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS