S100A9 / MRP14 Antibody (clone S36-48, Biotin)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Lyophilized |
$847.00each
Catalog Number: LS-C96227-100
Catalog Number: LS-C96227
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- Description
- MRP14 antibody LS-C96227 is a biotin-conjugated mouse monoclonal antibody to human MRP14 (S100A9). Validated for ELISA and IHC.
- Application
- ELISA, IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- 60B8AG | Calgranulin B | CFAG | CAGB | Calgranulin-B | Calprotectin L1H subunit | CGLB | L1Ag | MRP14 | NIF | p14 | Protein S100-A9 | LIAG | S100A9 | MAC387 | MRP-14
- UniProt Number
- P06702
- NCBI GenBank
- NM_002965 | NP_002956.1
- SwissProt
- P06702
Target
- Target
- Human S100A9 / MRP14
- Antigen Species
- Human
- Epitope
- The antigen is MRP14, the epitope is suspected in the central region of the peptide. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes. It is absent from all other blood cells. In cultured monocytes, maximum MRP14 expression is found after 3 - 4 days. Myeloid leukaemic cells have been found to be positive as well. Tissue sections: MRP14 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages synthesise MRP14 increasingly during the early stages of inflammation. A high MRP14 (and low MRP8) expression by macrophages was reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases like chronic rheumatoid arthritis, MRP8 and MRP14 positive cells consist of different subpopulations. During early inflammation endothelial cells are also positive with MRP8/14 determined by antibody 27E10. Specificity: Human: MRP14, granulocytes, stimulated monocytes and macrophages. Other: The antibody reacts with bovine spleen. It does not react with swine tissues.
- Gene Name
- S100A9
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- S36-48
- Origin Species
- Human
Immunogen
- Immunogen
- Cultured human monocytes
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Biotin
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at 4°C.
- Recommended Storage Buffer
- PBS