Immunohistochemistry of paraffin-embedded human brain tissue using RNF40 Antibody at dilution of 1:100
RNF40 / STARING Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general) |
| Reactivity: | Human |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C499673-50
Catalog Number: LS-C499673
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- Description
- STARING antibody LS-C499673 is an unconjugated rabbit polyclonal antibody to human STARING (RNF40). Validated for ELISA and IHC.
- Application
- ELISA, IHC
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- BRE1-B | KIAA0661 | RING finger protein 40 | RNF40 | Rb-associated protein | STARING | BRE1B | RBP95
- UniProt Number
- O75150
- NCBI GenBank
- NM_014771 | NP_055586.1
- SwissProt
- O75150
Target
- Target
- Human RNF40 / STARING
- Antigen Species
- Human
- Epitope
- Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.
- Gene Name
- RNF40
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human E3 ubiquitin-protein ligase BRE1B protein (471-724AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS