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Recombinant Monoclonal Rabbit anti-Mouse CR1 / CD35 Antibody (clone 8C12, CD35 (complement receptor 1), IHC, WB)

IHC on rat stomach.

Recombinant Monoclonal Rabbit anti-Mouse CR1 / CD35 Antibody (clone 8C12, CD35 (complement receptor 1), IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Flow Cytometry, Immunohistochemistry, Frozen, Immunoprecipitation, Western Blot
Reactivity:Mouse
Format:Liquid
See all Mouse CR1 / CD35 antibodies →
$551.00each
Catalog Number: LS-C777464-0.2

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Overview

Description
This CR1 / CD35 antibody is an unconjugated Rabbit/Mouse chimeric recombinant monoclonal antibody. Validated for Flo, IHC-Fr, IP, and WB.
Application
FC, IHC-F, IP, WB
Reactivity
Ms
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
C3b/C4b receptor | C3-binding protein | CD35 | C3BR | CR1 | Knops blood group antigen | C4BR | CD35 antigen | Complement receptor type 1 | KN
UniProt Number
P17927
SwissProt
P17927

Target

Target
Mouse CR1 / CD35
Antigen Species
Ms
Epitope
Recognises an epitope on CD35 (CR1, 190 kDa), but not on CD21 (CR2, 145-150 kDa), which are alternative splice variants of primary Cr2 gene transcripts.
Gene Name
CR1

Antibody

Host Species
Rb
Clonality
Recombinant Monoclonal
Clone
8C12
Isotype
IgG
Light Chain
κ
Origin Species
Hu

Immunogen

Immunogen
Purified murine CR1 protein.
Immunogen Type
Native

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
PBS, 0.02% ProClin™ 300.
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Prot A

Storage & Handling

Storage Conditions
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Recommended Storage Buffer
PBS
Promotion of the inflammatory response in mid colon of complement component 3 knockout mice. Yun Ju Choi, Ji Eun Kim, Su Jin Lee, Jeong Eun Gong, You Jeong Jin, Ho Lee, Dae Youn Hwang. Scientific reports. 2022 February;12:1700. PubMed: 35105928 PMC: PMC8807838

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