Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Formalin-fixed, paraffin-embedded human Pancreatic Cancer stained with Spectrin beta III Rabbit Recombinant Monoclonal (SPTBN2/2894R).
Recombinant Monoclonal Rabbit anti-Human SPTBN2 Antibody (clone SPTBN2/2894R, aa356-475, IHC, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751376-20
Catalog Number: LS-C751376
For bulk orders or custom formulations:
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- Description
- SPTBN2 antibody LS-C751376 is an unconjugated rabbit recombinant monoclonal antibody to human SPTBN2 (aa356-475). Validated for ELISA, Flow, IHC and WB.
- Application
- ELISA, FC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- Beta-III spectrin | GTRAP41 | SCA5 | Spectrin beta chain, brain 2 | SPTBN2 | Spinocerebellar ataxia 5 | KIAA0302
- Recommended Dilution: ELISA
- 2 - 4 ug/ml
- Recommended Dilution: FC
- 1 - 2 µg/10E6 cells
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- Recommended Dilution: WB
- 0.5 - 1 µg/ml
- UniProt Number
- O15020
- NCBI GenBank
- NM_006946 | NP_008877.1
- SwissProt
- O15020
Target
- Target
- Human SPTBN2
- Antigen Species
- Human
- Epitope
- Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin alpha and spectrin beta are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta I (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin beta III is highly homologous to both spectrin beta I and spectrin beta II. Spectrin beta III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.
- Gene Name
- SPTBN2
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- SPTBN2/2894R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant human SPTBN2 fragment (aa356-475). Antigen Molecular Weight: 246 kDa
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS