LSBio
Recombinant Monoclonal Rabbit anti-Human MMP9 / Gelatinase B Antibody (clone MMP9/2025R, Azide-free,Carrier-free, aa 603-614, IHC)

Formalin-fixed, paraffin-embedded human spleen stained with MMP9 Rabbit Recombinant Monoclonal Antibody (MMP9/2025R).

Recombinant Monoclonal Rabbit anti-Human MMP9 / Gelatinase B Antibody (clone MMP9/2025R, Azide-free,Carrier-free, aa 603-614, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all Human MMP9 / Gelatinase B antibodies →
$586.00each
Catalog Number: LS-C751271-100

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Overview

Description
Gelatinase B antibody LS-C751271 is an unconjugated rabbit recombinant monoclonal antibody to human Gelatinase B (MMP9) (aa 603-614). Validated for IHC.
Application
IHC-P
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
92kd gelatinase | 92 kDa gelatinase | Matrix metalloproteinase-9 | MMP9 | MMP-9 | CLG4B | Gelatinase B | GELB | Macrophage gelatinase | MANDP2
Recommended Dilution: IHC-P
0.5 - 1 µg/ml
UniProt Number
P14780
SwissProt
P14780

Target

Target
Human MMP9 / Gelatinase B
Antigen Species
Human
Epitope
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is down-regulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.
Gene Name
MMP9

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
MMP9/2025R
Isotype
IgG
Origin Species
Human

Immunogen

Immunogen
Recombinant fragment (around aa 603-614) of human MMP-9 protein. Antigen Molecular Weight: 92 kDa
Immunogen Type
Recombinant Protein Fragment

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS
Concentration
1 mg/mL
Preservative
No
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at -20°C to -80°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.