Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Formalin-fixed, paraffin-embedded Human Tonsil stained with IgG4 Recombinant Rabbit Monoclonal Antibody (IGHG4/2042R).
Recombinant Monoclonal Rabbit anti-Human IGHG4 Antibody (clone IGHG4/2042R, Azide-free,Carrier-free, IHC)
Secondary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751199-100
Catalog Number: LS-C751199
For bulk orders or custom formulations:
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- Description
- IGHG4 antibody LS-C751199 is an unconjugated rabbit recombinant monoclonal antibody to human IGHG4. Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Secondary Antibodies
- Alternative Names
- IGHG4
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P01861
- SwissProt
- P01861
Target
- Target
- Human IGHG4
- Antigen Species
- Human
- Epitope
- The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Reportedly, a large population of patients with recurrent respiratory tract infection has low IgG4 concentrations. IgG4-related sclerosing disease has been recognized as a systemic disease entity characterized by an elevated serum IgG4 level, sclerosing fibrosis, and diffuse lympho-plasmacytic infiltration with the presence of many IgG4-positive plasma cells. IgG4 is overexpressed in inflammatory pseudo-tumor (IPT) and under expressed in inflammatory myofibroblastic tumor (IMT). In pulmonary nodular lymphoid hyperplasia (PNLH), there are an increased number of IgG4+ plasma cells.
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- IGHG4/2042R
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant full-length human IGHG4 protein. Antigen Molecular Weight: 150 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS