LSBio
Recombinant Monoclonal Rabbit anti-Human GP2 Antibody (clone GP2/2569R, aa35-179, IHC)

Formalin-fixed, paraffin-embedded Human Pancreas stained with GP2 Recombinant Rabbit Monoclonal Antibody (GP2/2569R).

Recombinant Monoclonal Rabbit anti-Human GP2 Antibody (clone GP2/2569R, aa35-179, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all Human GP2 antibodies →
$379.00each
Catalog Number: LS-C751160-20

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Overview

Description
GP2 antibody LS-C751160 is an unconjugated rabbit recombinant monoclonal antibody to human GP2 (aa35-179). Validated for ELISA and IHC.
Application
ELISA, IHC-P
Reactivity
Hu
Nonreactive Species
Mouse
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
gp2 | ZAP75
Recommended Dilution: ELISA
2 - 4 ug/ml
Recommended Dilution: IHC-P
1 - 2 µg/ml
UniProt Number
P55259
SwissProt
P55259

Target

Target
Human GP2
Antigen Species
Human
Epitope
GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Gene Name
GP2

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
GP2/2569R
Isotype
IgG
Origin Species
Human

Immunogen

Immunogen
Recombinant human GP2 protein fragment (around aa35-179). Antigen Molecular Weight: 59 kDa
Immunogen Type
Recombinant Protein Fragment

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.