LSBio
Recombinant Monoclonal Mouse anti-Human MLANA / Melan-A Antibody (clone rMLANA/788, Azide-free,Carrier-free, IHC)

Formalin-fixed, paraffin-embedded human Melanoma stained with MART-1 Mouse Recombinant Monoclonal Antibody (rMLANA/788).

Recombinant Monoclonal Mouse anti-Human MLANA / Melan-A Antibody (clone rMLANA/788, Azide-free,Carrier-free, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Recombinant Monoclonal
Applications:Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all Human MLANA / Melan-A antibodies →
$586.00each
Catalog Number: LS-C751136-100

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Overview

Description
Melan-A antibody LS-C751136 is an unconjugated mouse recombinant monoclonal antibody to human Melan-A (MLANA). Validated for IHC.
Application
IHC-P
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
Antigen LB39-AA | Antigen SK29-AA | Melan-A | MLANA | Protein Melan-A | MART-1 | MART1 | Melan A
Recommended Dilution: IHC-P
0.5 - 1 µg/ml
UniProt Number
Q16655
SwissProt
Q16655

Target

Target
Human MLANA / Melan-A
Antigen Species
Human
Epitope
This antibody recognizes a protein doublet of 20-22 kDa , identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Gene Name
MLANA

Antibody

Host Species
Mouse
Clonality
Recombinant Monoclonal
Clone
rMLANA/788
Isotype
IgG1
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length hMART-1 protein. Antigen Molecular Weight: 20-22 kDa (doublet)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS
Concentration
1 mg/mL
Preservative
No
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at -20°C to -80°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

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