LSBio
Recombinant Monoclonal Mouse anti-Human MCAM / CD146 Antibody (clone rMUC18/1130, Azide-free,Carrier-free, IHC)

Formalin-fixed, paraffin-embedded human Tonsil stained with MUC18 Mouse Recombinant Monoclonal Antibody (rMUC18/1130).

Recombinant Monoclonal Mouse anti-Human MCAM / CD146 Antibody (clone rMUC18/1130, Azide-free,Carrier-free, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Recombinant Monoclonal
Applications:Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all Human MCAM / CD146 antibodies →
$586.00each
Catalog Number: LS-C751265-100

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Overview

Description
CD146 antibody LS-C751265 is an unconjugated mouse recombinant monoclonal antibody to human CD146 (MCAM). Validated for IHC.
Application
IHC-P
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
CD146 | CD146 antigen | Gicerin | Melanoma adhesion molecule | MCAM | MUC18 | p1h12
Recommended Dilution: IHC-P
0.5 - 1 µg/ml
UniProt Number
P43121
SwissProt
P43121

Target

Target
Human MCAM / CD146
Antigen Species
Human
Epitope
Mel-CAM belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Gene Name
MCAM

Antibody

Host Species
Mouse
Clonality
Recombinant Monoclonal
Clone
rMUC18/1130
Isotype
IgG1
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length human MUC18 protein. Antigen Molecular Weight: 130 kDa
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS
Concentration
1 mg/mL
Preservative
No
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at -20°C to -80°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

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