RAB5A / RAB5 Antibody (FITC)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C499649-50

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Description: RAB5 antibody LS-C499649 is an FITC-conjugated rabbit polyclonal antibody to human RAB5 (RAB5A). Validated for ELISA.
Application: ELISA
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: Ras-related protein Rab-5A | RAS-associated protein RAB5A | RAB5 | RAB5A
UniProt Number: P20339
NCBI GenBank: NM_004162 | NP_004153.2
SwissProt: P20339

Target: Human RAB5A / RAB5
Antigen Species: Human
Epitope: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3 (By similarity).
Gene Name: RAB5A

Storage Conditions: Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer: PBS

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