PTPN11 / SHP-2 / NS1 Antibody (Biotin)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay |
| Reactivity: | Human |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C500247-50
Catalog Number: LS-C500247
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- Description
- NS1 antibody LS-C500247 is a biotin-conjugated rabbit polyclonal antibody to human NS1 (PTPN11 / SHP-2). Validated for ELISA.
- Application
- ELISA
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Bptp-3 | BPTP3 | CFC | Csw | Corkscrew csw | Gene corkscrew | Phosphatase corkscrew | PTP-2C | SHP2 | PTP-1D | PTP2C | PTPN11 | SHP-2 | SHPTP2 | Noonan syndrome 1 | SH-PTP2 | SH-PTP3
- UniProt Number
- Q06124
- NCBI GenBank
- NM_002834 | NP_002825.3
- SwissProt
- Q06124
Target
- Target
- Human PTPN11 / SHP-2 / NS1
- Antigen Species
- Human
- Epitope
- Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).
- Gene Name
- PTPN11
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Tyrosine-protein phosphatase non-receptor type 11 protein (246-520AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Biotin
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS