Immunohistochemistry of paraffin-embedded human small intestine tissue using PTBP1 Antibody at dilution of 1:100

PTBP1 Antibody

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C498459-50

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Description: PTBP1 antibody LS-C498459 is an unconjugated rabbit polyclonal antibody to human PTBP1. Validated for ELISA and IHC.
Application: ELISA, IHC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: HnRNP I | HNRNPI | HNRPI | PTB | PPTB | PTB2 | PTB4 | RNA-binding protein | HNRNP-I | PTB-1 | PTB-T | PTB3 | PTBP1
UniProt Number: P26599
NCBI GenBank: NM_031991 | NP_114368.1
SwissProt: P26599

Target: Human PTBP1
Antigen Species: Human
Epitope: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
Gene Name: PTBP1