Human brain tumour lysate probed with Mouse anti-AMPK alpha 1/2
PRKAA1 / AMPK Alpha 1 Antibody (N-Terminus, clone 84.1)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry, Frozen, Immunoprecipitation, Western Blot |
| Reactivity: | Fruit Fly |
| Format: | Liquid |
$296.00each
Catalog Number: LS-C188362-0.1
Catalog Number: LS-C188362
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- Description
- AMPK Alpha 1 antibody LS-C188362 is an unconjugated mouse monoclonal antibody to drosophila AMPK Alpha 1 (PRKAA1) (N-Terminus). Validated for ELISA, IF, IHC, IP and WB.
- Application
- ELISA, IF, IHC-F, IP, WB
- Reactivity
- Dros
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- ACACA kinase | AMPK alpha 1 | AMPK alpha-1 chain | Acetyl-CoA carboxylase kinase | AMPKa1 | AMPK subunit alpha-1 | AMPK | AMPK1 | Tau-protein kinase PRKAA1 | HMGCR kinase | PRKAA1
- Recommended Dilution: WB
- 1:100 - 1:1000
- UniProt Number
- Q13131
- NCBI GenBank
- NM_006251 | NP_006242.5
- SwissProt
- Q13131
Target
- Target
- Drosophila PRKAA1 / AMPK Alpha 1
- Antigen Species
- Fruit Fly
- Epitope
- Recognizes both the alpha 1 and the alpha 2 isoforms of AMP-activated protein kinase (AMPK). AMPK is a highly conserved heterotrimeric protein kinase found in all eukaryotes. The heterotrimeric complex exists as multiple isoforms and consists of a catalytic alpha subunit, which is stabilized by non-catalytic regulatory beta- and gamma- subunits. AMPK plays a vital role in maintaining cellular energy homeostasis and is activated by rising levels of AMP under conditions of hypoxia, ischemia, exercise, low glucose levels. AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes. Recent studies suggest that AMPK functions as a suppressor of cell proliferation of both malignant and normal cells.
- Gene Name
- PRKAA1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 84.1
- Isotype
- IgG2a
Immunogen
- Immunogen
- 29 AA peptide within the N-Terminus catalytic domain of Drosophila AMPK alpha.
- Immunogen Type
- Peptide
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS