LSBio
Polyclonal Rabbit anti-Naja kaouthia CVF Antibody (WB)

Western Blot Positive WB detected in Recombinant protein All lanes: C3 antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution predicted band size: 45 kDa observed band size: 45 kDa

Polyclonal Rabbit anti-Naja kaouthia CVF Antibody (WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity:Reptile
Format:Liquid
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$300.00each
Catalog Number: LS-C501604-50

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Overview

Description
CVF antibody LS-C501604 is an unconjugated rabbit polyclonal antibody to naja kaouthia CVF. Validated for ELISA and WB.
Application
ELISA, WB
Reactivity
Rept
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Recommended Dilution: WB
1:500 - 1:5000
UniProt Number
Q91132
SwissProt
Q91132

Target

Target
Naja kaouthia CVF
Antigen Species
Reptile
Epitope
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Naja kaouthia Cobra venom factor protein (733-984AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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